Part 3: Coffee & Psilocybin: Microdosing, Macrodosing & Neurochemistry

Can you mix coffee with psilocybin? Studies suggest caffeine and psilocybin act on overlapping serotonin and dopamine pathways but with opposite energetic profiles. Here’s how timing, dosage, and neurochemistry determine whether the combo enhances focus or increases anxiety. (Not medical advice.)
Part 2: Coffee + Ayahuasca: Timing, Risks & Guidelines

Can you drink coffee before or after an ayahuasca ceremony? Science shows caffeine mildly inhibits MAO enzymes, while ayahuasca’s β-carbolines strongly block MAO-A. Combining them may elevate blood pressure, heart rate, and anxiety. Here’s what the research says—and how to time caffeine safely. (Not medical advice.)
Part 1: Coffee & Psychedelics: What Science Actually Says

Can coffee mix safely with psychedelics? Published research on caffeine, ayahuasca, and psilocybin suggests caution. Coffee mildly inhibits MAO enzymes and raises blood pressure. Ayahuasca temporarily blocks MAO-A. Psilocybin alters serotonin signaling. Here’s what science—and only science—currently shows. (Not medical advice.)
Part 5 – How Much Coffee Is Too Much? Finding the Brain-Boosting Sweet Spot

Research shows coffee may enhance brain health — but how much is too much? Learn the optimal coffee intake for cognitive benefits without the downsides.
Part 4 – Coffee and Mental Performance: How It Impacts Memory, Focus, and Mood

Coffee doesn’t just wake you up — it can enhance memory, boost focus, and improve mood. Here’s how your daily cup affects mental performance, according to research.
Part 3 – Can Coffee Help Prevent Alzheimer’s Disease? Here’s What the Research Says

Studies show coffee may reduce Alzheimer’s disease risk. It achieves this by lowering inflammation, supporting brain function, and slowing amyloid plaque buildup. Here’s what science says.
Part 2 – How Coffee Supports Brain Chemistry and Neuroprotection

Beyond the caffeine boost, coffee may protect your brain at the cellular level. It influences neurotransmitters and reduces inflammation. Coffee even supports long-term neuroprotection. Here’s how.
Part 1 – Coffee and Cognitive Decline: What the Research Shows

Research shows coffee may do more than wake you up — it may protect your brain, reduce cognitive decline, and even lower the risk of dementia. Here’s what the science says.
How Coffee Protects Your Liver (According to Science)

Discover how coffee may help reduce your risk of liver disease, fibrosis, and cirrhosis — backed by research and meta-analyses. Here’s how each cup supports your health.