Part 3: Coffee & Psilocybin: Microdosing, Macrodosing & Neurochemistry
Can you mix coffee with psilocybin? Studies suggest caffeine and psilocybin act on overlapping serotonin and dopamine pathways but with opposite energetic profiles. Here’s how timing, dosage, and neurochemistry determine whether the combo enhances focus or increases anxiety. (Not medical advice.)