Part 1: Coffee & Psychedelics: What Science Actually Says
Can coffee mix safely with psychedelics? Published research on caffeine, ayahuasca, and psilocybin suggests caution. Coffee mildly inhibits MAO enzymes and raises blood pressure. Ayahuasca temporarily blocks MAO-A. Psilocybin alters serotonin signaling. Here’s what science—and only science—currently shows. (Not medical advice.)